刘派个人简历
教育/工作经历
天津工业大学，材料科学与工程学院，副教授
2021.12-至今
研究课题：有机荧光材料在光动力治疗/声动力治疗抗肿瘤中的应用
北京理工大学，博士
2016.9-2020.12 材料学院 材料科学与工程（“双一流学科”）
研究课题：聚集诱导发光材料用于肿瘤识别
韩国高丽大学（世界QS排名：69），联合培养博士
2019.10-2020.10 化学学院 国家公派建设高水平大学项目联合培养博士生
研究课题：肿瘤光动力治疗及免疫死亡过程
北京理工大学，硕士
2014.9-2016.7 生命学院 生物医学与工程
研究课题：聚集诱导发光材料用于快速医疗中的离子检测
华南理工大学，学士
2010.9-2014.6 轻工与食品学院 资源科学与工程
研究课题：半纤维素/纳米金材料的绿色制备和应用
研究经历
主要研究方向为：
1. 聚集诱导发光有机材料的设计、合成与制备
2. 有机光敏剂在光动力治疗，声动力治疗中的应用
3. 耐乏氧光动力静电纺丝膜构筑用于糖尿病足伤口修复研究
主持项目：
横向项目，《一种可穿戴的睡眠调控装备》，2025.1-2026.12，100万，主持。
河北省自然科学基金青年项目，《聚集诱导发光声敏剂的设计策略凝练及其在糖尿病足敷料中的应用》，2024.1-2026.12，5万，主持。
国家自然科学基金青年项目，《高吸光系数聚集诱导发光I型光敏剂开发及其在肿瘤免疫治疗中的应用》，2023.1-2025.12，30万，主持。
天津市自然科学基金多元投入青年项目，《聚集诱导发光性质的荧光可视化肿瘤冷冻消融探针开发》，2021.9-2023.9，6万，主持。
中央引导地方科技发展专项，《一站式止血和抗菌修复的耐乏氧光动力纤维膜及其性能研究》，2022.1-2023.12，50万，主持。
指导国家级大学生本科创新创业计划《一种耐肿瘤乏氧的有机敏化剂在光声联合免疫诊疗中的应用研究》1项。
科研成果
1. Yuming Chang, Fangpu Liu, Yaning Li, Mengyan Tian, Xinyue Zhao, Yucong Li, Pai Liu*. Tailored one-stop dressing for diabetic wounds utilizing AIE electrospun photodynamic film. Chemical Engineering Journal, 2025, 511, 161989.
Pai Liu*, Xinyue Zhao, Jiayu Cao, Mengyan Tian, Yaning Li, Chunyan Ma, Tianyue Yang,Yi Liu*. Potentiating Light-Harvesting Tactics Through an A-D-A Structure: Repolarization of tumor-associated macrophages through phototherapy. Journal of Materials Chemistry B, 2024,12, 7870-7878.
2. Yaning Li, Mengyan Tian, Tianyue Yang, Jiayu Cao, Hongli Chen, Jun Guo, Pai Liu*, Yi Liu*. Enhanced population of excited single state strategy: irradiation and ultrasound dual-response and host tumor-driven nano-sensitizers construction in triple synergistic therapy. Nano Research, 2024, 17, 5501-5511.
3. Mengyan Tian, Yucong Li, Yaning Li, Tianyue Yang, Hongli Chen, Jun Guo,Yi Liu*, Pai Liu*. Sonodynamic therapy-driven immunotherapy: constructing aie organic sonosensitizers using an advanced receptor-regulated strategy. Small, 2024, 2400654.
4. Pai Liu, Tianyue Yang, Yaning Li, Jun Guo, Shulan Li, Hongli Chen* and Yi Liu*. Nanomaterial-based sonosensitizers: from exemplary design towards purposeful improvement. Materials Chemistry Frontiers, 2023, 7, 985-1003.
5.Shisheng Cui, Shuangxiong Dai, Na Lin, Xinghui Wu, Jianbing Shi, Bin Tong, Pai Liu*, Zhengxu Cai* and Yuping Dong. Constructing hypoxia-tolerant and host tumor-enriched AIE photosensitizer for suppressing malignant tumors relapse and metastasis. Small, 2022, 18, 2203825.
6. Hongli Chen, Yuanhao Cai, Shujie Sun, Zhenhua Pan, Zhibo Han, Pai Liu*, Yi Liu*. Repair effect of photobiomodulation combined with human umbilical cord mesenchymal stem cells on rats with acute lung injury [J]. Journal of Photochemistry and Photobiology B: Biology, 2022, 234, 112541.
7. Pai Liu1, Fei Ren1, Subin Son1, Myung Sun Ji, Peng Li, Zhengxu Cai, Jianbing Shi*, Yi Liu, Yuping Dong, Jong Seung Kim*. Mitochondrial targeted AIEgen phototheranostics for bypassing immune barrier via encumbering mitochondria functions. Biomaterials, 2022, 283, 121409.
8. Pai Liu1, Weiqiang Fu1, Peter Verwilst, Miae Won, Jinwoo Shin, Zhengxu Cai*, Bin Tong, Jianbing Shi, Yuping Dong*, and Jong Seung Kim*. 《MDM2-associated Clusterization-Triggered Emission and Apoptosis Induction Effecturated by a Theranostic Spiropolymer》Angewandte Chemie International Edition, 2020, 132, 8513-8517
9. Zhiyuan He1, Pai Liu1,Shizhong Zhang, Jie Yan, Mengni Wang, Zhengxu Cai,* Jianjun Wang,*
and Yuping Dong. Freezing Induced Turn-on Modality for Real-time Imaging in Cryosurgery, Angewandte Chemie International Edition, 2019, 58, 3834-3837.
10. Pai Liu, Didi Chen, Yuanhang Wang, Xiaoying Tang, Hanjun Li*, Jianbing Shi, Bin Tong, Yuping Dong*. A highly sensitive “turn-on” fluorescent probe with an aggregation-induced emission characteristic for quantitative detection of γ-globulin, Biosensors and Bioelectronics, 2016, 23, 982-987.
11. Pai Liu, Wangyang Li, Shuai Guo, Dongrui Xu, Mengni Wang, Jianbing Shi*, Zhengxu Cai, Bin Tong, and Yuping Dong*.《Application of a Novel “Turn-on” Fluorescent Material to the Detection of Aluminum Ion in Blood Serum》, ACS Applied Material and Interfaces, 2018, 10, 23667-23673.
12.Fei Ren1,Pai Liu1, Yu Gao, Jianbing Shi*, Bin Tong, Zhengxu Cai and Yuping Dong*. 《Real time bioimaging for mitochondria by taking the aggregation process of aggregation-induced emission near-infrared dyes with wash-free staining》, Materials Chemistry Frontiers, 2019, 3, 57-63.
13. Miae Won1, Mingle Li1, Hyeong Seok Kim1, Pai Liu1, et.al. Visible to Mid IR: A Library of Multispectral Diagnostic Imaging. Coordination Chemistry Reviews, 2021, 426, 213608-213631.